The Science of Addiction by
An updated and expanded edition on the roles that brain function and genetics play in addiction. Over the past 10 years, neurobiologic and genetic research has provided an increased understanding of what causes drug addiction in the brain's reward pathway. Knowing this leads to a better understanding of how it may be treated and even reversed in those who successfully overcome the disease. This is especially true with addiction's possible precursors of mild to moderate substance use disorders. These latter disorders can usually be treated more easily by less intensive models of "treatment" that do not require actual brain chemistry re-regulation over time. In this new edition, there are updated scientific references to support addiction as a medical brain disease, using the prevailing neurobiology, genetics, and psychological scientific literature. We now have more psychosocial and medicinal methods for reversing abnormal brain chemistry during drug addiction. There are also more effective intervention, counseling, and motivating methods (SBIRT, motivational interviewing) for overcoming resistance to treatment and resistance to change than were able to be discussed when the first edition was published over a decade ago. Here, readers will find a fully-updated glossary of terms, additional abbreviations, and updated appendices. These will aid in clarifying the somewhat lengthy and science-based upgrades in our knowledge of neuroscience and genetics research that are so critical in understanding why addiction is such a serious and tough-to-treat disease. Utilizing the same easy-to-read language that was a hallmark of the earlier edition, Erickson keeps the science understandable yet comprehensive--appropriate for health professionals as well as lay readers who need and want this critical information.
Never Enough by
A NEW YORK TIMES BESTSELLER From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a "cure" for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.
The Urge by
Named a Best Book of the Year by The New Yorker and The Boston Globe An authoritative, illuminating, and deeply humane history of addiction--a phenomenon that remains baffling and deeply misunderstood despite having touched countless lives--by an addiction psychiatrist striving to understand his own family and himself "Carl Erik Fisher's The Urge is the best-written and most incisive book I've read on the history of addiction. In the midst of an overdose crisis that grows worse by the hour and has vexed America for centuries, Fisher has given us the best prescription of all: understanding. He seamlessly blends a gripping historical narrative with memoir that doesn't self-aggrandize; the result is a full-throated argument against blaming people with substance use disorder. The Urge is a propulsive tour de force that is as healing as it is enjoyable to read." --Beth Macy, author of Dopesick Even after a decades-long opioid overdose crisis, intense controversy still rages over the fundamental nature of addiction and the best way to treat it. With uncommon empathy and erudition, Carl Erik Fisher draws on his own experience as a clinician, researcher, and alcoholic in recovery as he traces the history of a phenomenon that, centuries on, we hardly appear closer to understanding--let alone addressing effectively. As a psychiatrist-in-training fresh from medical school, Fisher was soon face-to-face with his own addiction crisis, one that nearly cost him everything. Desperate to make sense of the condition that had plagued his family for generations, he turned to the history of addiction, learning that the current quagmire is only the latest iteration of a centuries-old story: humans have struggled to define, treat, and control addictive behavior for most of recorded history, including well before the advent of modern science and medicine. A rich, sweeping account that probes not only medicine and science but also literature, religion, philosophy, and public policy, The Urge illuminates the extent to which the story of addiction has persistently reflected broader questions of what it means to be human and care for one another. Fisher introduces us to the people who have endeavored to address this complex condition through the ages: physicians and politicians, activists and artists, researchers and writers, and of course the legions of people who have struggled with their own addictions. He also examines the treatments and strategies that have produced hope and relief for many people with addiction, himself included. Only by reckoning with our history of addiction, he argues--our successes and our failures--can we light the way forward for those whose lives remain threatened by its hold. The Urge is at once an eye-opening history of ideas, a riveting personal story of addiction and recovery, and a clinician's urgent call for a more expansive, nuanced, and compassionate view of one of society's most intractable challenges.
Substance abuse refers to the harmful or hazardous use of psychoactive substances, including alcohol and drugs. It occurs when someone uses these substances in ways that are excessive, unhealthy, or outside of medical guidelines, leading to negative consequences for their health, relationships, and daily functioning.
Key characteristics of substance abuse include:
Substance abuse can lead to addiction, but the two are not the same. Abuse refers to problematic use, while addiction involves physical or psychological dependence. Treatment typically includes counseling, support groups, and sometimes medication.
Addiction is a chronic, relapsing condition characterized by the compulsive use of a substance or engagement in a behavior despite harmful consequences. It affects the brain’s reward system, leading to intense cravings, loss of control, and continued use even when it negatively impacts health, relationships, and daily life.
Key characteristics of addiction include:
Addiction can involve substances like alcohol, nicotine, and drugs, as well as behaviors like gambling, gaming, or shopping. It is considered a medical condition that can be treated through therapy, medication, and support systems.